Co-crystal technology is had recently got rapid popularity in the pharmaceutical field. Co-crystals generally contains two or more molecular components. Among them one is active pharmaceutical ingredient (API) and other is crystal former bonded with each other generally by hydrogen bond. Co-crystallization changes the molecular interactions and composition of API, and is considered better alternative to gate desired drug properties. Co-crystals provide several advantages over original drug molecule. It can overcome several issues of drug molecule such as solubility, stability and bioavailability. Co-crystal is generally formed when it is thermodynamically more stable than the crystals of original API and crystal former. In future vital role can be played by co-crystals in pharmaceutical industry.
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